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HYDIN Antibody, HRP conjugated

Datasheet
Code CSB-PA670104LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HYDIN Polyclonal antibody
Uniprot No.
Q4G0P3
Target Names
HYDIN
Alternative Names
CILD5 antibody; Hydin antibody; HYDIN axonemal central pair apparatus protein antibody; HYDIN_HUMAN antibody; HYDIN1 antibody; HYDIN2 antibody; Hydrocephalus-inducing protein homolog antibody; PPP1R31 antibody; Protein phosphatase 1 regulatory subunit 31 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Hydrocephalus-inducing protein homolog protein (101-400AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Customer Reviews and Q&A

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Target Background

Function
Required for ciliary motility.
Gene References into Functions
  1. Three loci with high mutation frequencies, the 138665410 FOXL2 gene variant, the 23862952 MYH6 gene variant, and the 71098693 HYDIN gene variant were found to be significantly associated with sporadic Atrial Septal Defect (P<0.05); variants in FOXL2 and MYH6 were found in patients with isolated, sporadic Atrial Septal Defect (P<5x10-4). PMID: 29505555
  2. The results suggest frequent and coordinated adaptive immune responses against HYDIN variants in patients with cancer. PMID: 24777681
  3. We have found that the human HYDIN locus has been very recently duplicated, with a nearly identical 360-kb paralogous segment inserted on chromosome 1q21.1 PMID: 16938426
Involvement in disease
Ciliary dyskinesia, primary, 5 (CILD5)
Subcellular Location
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme.
Database Links

HGNC: 19368

OMIM: 608647

KEGG: hsa:54768

STRING: 9606.ENSP00000314736

UniGene: Hs.351914

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